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Invitation to Malvern Panalytical Biophysical Characterization Seminars 23-24th May on Novel Drug Discovery & Delivery systems

Seminar TOPIC: Novel Drug Discovery & Delivery systems

Biophysical Characterization Seminar presented by Malvern Panalytical experts

Biophysical characterization of macromolecules is an essential step in the development of new drugs. It contains analysis of the basic properties, e.g. stability and homogeneity, as well as the investigation of interaction between biomolecules and their binding partners, both natural and artificial ones. Malvern Panalytical offers a broad range of instruments suitable for this type of experiments, with several of them installed and available for scientific community in the campus of Masaryk University in Brno or at BIOCEV in Prague (Vestec).

We will show you for the first time UNIQUE Grating-Coupled Interferometry (GCI) technology for evaluation of affinity and binding kinetics with its many advantages over well known Surface plasmon resonance (SPR) technology. Creoptix application specialist will explain how to get a binding kinetics in hours compared to days with SPR (for more advantages see points below). You will learn how the GCI technology speeds up and complements other technologies such as ITC and DSC microcalorimetry. Other application specialists will explain which complex information you can get from size exclusion chromatography with advanceand detectors, how to test stability, agglomeration behaviour, particle size or loading of drug delivery systems such as viral vectors and lipidic nanoparticles using dynamic light scattering or nanoparticle tracking analyses and many more.

The one day event will be similar for both Prague 23.5. and Brno 24.5. locations except the larger focus on GCI technology and DLS measurements in Prague at the end of the event compared to availability of all the instruments at the Brno location (except GCI technology). There will be chance to discuss with experts your results, research or issues and have a look into software at the end of events.

The seminar will include also coffee breaks and lunch free of charge. We hope you will enjoy the wealth of knowledge we bring to CZ.

 

Program of individual days:

23rd of May 2023, Prague

Masarykova kolej, Thákurova 1, Praha 6

08:30  Coffee and welcome

09:00  Biophysical characterization – The best of Malvern Panalytical and CLS Dr. Agatha Rosenthal, BioScience Application Specialist
09:30
 SEC: the OMNISEC system & Applications examples in bio- pharma Dr. Serena Agostini, Sales Specialist, Malvern Panalytical

10:15  Coffee break

10:30  Pushing the Boundaries in Biomolecular Interaction Analysis with the Creoptix WAVEsystem and waveRAPID – From Biologics to Fragment-Based Drug Discovery Dr. Andrea Moretti, Field Application Scientist, Creoptix

11:30  Lunch

12:30  Biophysical Characterization of Viral and Lipid-Based Vectors for Vaccines and Therapeutics with Light Scattering and Calorimetric Techniques Dr. Agatha Rosenthal, BioScience Application Specialist
13:30
 Analytical characterization of LNP vectors, Dr. Agatha Rosenthal, BioScience Application Specialist
14:15
  Coffee break

14:30  Groups:

1) Creoptix Wave – Kinetic data evaluation demonstration,

2) Zetasizer Ultra Red demonstration with possible size, zeta and nanoparticle concentration measurements

3) Individual discussions with experts, SW demonstrations.

16:00  End of the event

REGISTRATION FORM TO PRAGUE LOCATION

 

24th of May, Brno – CEITEC MUNI Campus Bohunice

Address: Masarykova Univerzita (MUNI), Kamenice 753/5, Brno, building E35/211

Organized in collaboration with Core Facility Biomolecular Interactions and Crystallography

08:30  Coffee and welcome

09:00  Biophysical characterization – The best of Malvern Panalytical and CLS Dr. Agatha Rosenthal, BioScience Application Specialist
9:30
 Analytical characterization of LNP vectors, Dr. Agatha Rosenthal, BioScience Application Specialist

10:15  Coffee break

10:30  Biophysical Characterization of Viral and Lipid-Based Vectors for Vaccines and Therapeutics with Light Scattering and Calorimetric Techniques Dr. Agatha Rosenthal, BioScience Application Specialist

11:30  Pushing the Boundaries in Biomolecular Interaction Analysis with the Creoptix WAVEsystem and waveRAPID – From Biologics to Fragment-Based Drug Discovery Dr. Andrea Moretti, Field Application Scientist, Creoptix

12:30  Lunch

13:30  SEC: the OMNISEC system & Applications examples in bio- pharma Dr. Serena Agostini, Sales Specialist, Malvern Panalytical

14:15  Coffee break

14:45  Groups – Tour through labs and software demonstrations: MicroCal ITC, MicroCal DSC, OMNISEC, NanoSight NS300 and Zetasizer Ultra Red (possible demonstration and sample measurement) at CEITEC MUNI and Institute of biochemistry MUNI.

16:00  End of the event

REGISTRATION FORM TO BRNO LOCATION